BASIC FACTS ABOUT ANEMIA

• A recent study documented that anemia affects 27% of the global population, or nearly 2 billion people. 

• Although a recent study found that Iron Deficiency Anemia (IDA) was the most common cause of anemia, other causes are also important, vary considerably in different populations, and require different interventions. 

• There has been particular concern about young children and pregnant women in less developed countries.

• Anemia is a significant global health issue that has increased in 8 countries and is associated with high mortality and morbidity.

• Anemia is also an issue in older individuals and non-pregnant women.

• In adolescents with heavy menstrual bleeding or abnormal uterine bleeding, IDA is a common but under-recognized complication.

• A recent retrospective study found that aortic stenosis patients undergoing transcatheter aortic valve implantation (TAVI) commonly have comorbid anemia, which is predictive of mortality or re-hospitalization in these patients.

• Celiac disease is best known for causing gastrointestinal symptoms triggered by gluten consumption, but it may also present with extra-intestinal manifestations, of which IDA is the most common.

• Prevalence of iron deficiency, which is the precursor of IDA, is highest in female adolescents aged 16 to 19 years, providing a setting for the development of anemia following excessive blood loss during menses. Yet routine screening for IDA is not recommended.

• In a retrospective study of 549 patients undergoing TAVI, at baseline, 45% of the patients were anemic. 

• A recent survey of US physicians found that PCPs are likely under-testing for celiac disease in patients with unexplained IDA.